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Study of IgA Deficiency in GSDs (anyone want to participate?
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Old 07-05-2006, 10:39 AM   #1 (permalink)
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Study of IgA Deficiency in GSDs (anyone want to participate?

Is anyone interested in participating in a study on GSDs? Here's some info:

"IgA deficiency in German Shepherd Dogs

Immunoglobulins (Ig) are proteins produced by the immune system, which help to prevent and fight infectious diseases. Four classes of immunoglobulins are known: IgG, IgM, IgA, and IgE. They have different biochemical structures and are specialized for different tasks. Immunoglobulin A is important in protecting mucosal surfaces of the body, including the respiratory, intestinal and urogenital tract.

There is evidence that IgA deficiency might be inherited. Dog breeds that are affected include German Shepherd Dogs, Chinese Shar Peis, Beagles, Irish Wolf Hounds, and Cocker Spaniels. ... We are looking for purebred German Shepherd Dogs at least 12 months of age from multi-generational family groups. ..."

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The following web site has more information, and contact info.

http://www.cvm.tamu.edu/gilab/IgA%20information.shtml

I'm going to participate with Jak, even though he doesn't currently show any signs of the disease. They need both dogs that do show signs and dogs that don't, so they'll have a comparison basis. You have to collect 4 fecal samples at specific times, and send those, along with 5mL of blood, to the group doing the study (they pay shipping and send you all the necessary materials).
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